EthicsPoint - AstraZeneca

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FIRST In general, you should seek to address your concerns with your manager. If you believe this is not appropriate, you may also contact your Human Resources, Legal department, or Compliance representative.

MESSAGE FROM DAVID BRENNAN

Chief Executive Officer

CODE OF CONDUCT

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HOW TO ASK A QUESTION OR RAISE A CONCERN

ANYONE WHO RAISES A CONCERN ABOUT A POSSIBLE COMPLIANCE BREACH IN GOOD FAITH WILL BE SUPPORTED BY MANAGEMENT, AND WILL NOT BE SUBJECT TO RETALIATION. ANY ACT OR THREAT OF RETALIATION WILL IN ITSELF BE CONSIDERED A SERIOUS VIOLATION OF THIS CODE.

You may at some time come across a situation that appears to violate an AstraZeneca policy. Everyone has a duty to report any suspected violation promptly.

In general, you should first seek to address your concerns with your manager. If you believe this is not appropriate, you may also contact your Human Resources, Legal Department or Compliance representative. If you prefer to contact someone outside your area, you may use any of the following contacts:

AZETHICS LINE See page 20 for the telephone number to call in your country (MedImmune and Aptium Oncology employees should also refer to page 20 for information on reporting within their organisations)

WEBSITE AZethics.com

EMAIL GlobalCompliance@astrazeneca.com

POSTAL ADDRESS Global Compliance Officer, AstraZeneca PLC, 15 Stanhope Gate, London W1K 1LN, United Kingdom

If the concern relates to accounting, internal accounting controls or auditing matters, you may contact the AZethics line, the Global Compliance Officer or the VP, Group Internal Audit.

You can provide information anonymously if you prefer, and if your local laws so permit. In all instances, every effort will be made to ensure that information relating to a reported violation is kept confidential and communicated on a need-to-know basis only.

Group Internal Audit, which reports to the Board of Directors, works closely with the Global Compliance Officer to ensure that confidentiality and impartiality are maintained in the overall process.

The above procedures can also be followed if you have a question, or are seeking clarification about any aspect of this Code and its supporting policies.

The AZethics line and AZethics.com are managed by a third party on AstraZeneca's behalf. When you ask a question or raise a concern, you will be asked to provide details and whether you wish to disclose your contact information. AstraZeneca UK Limited may record this information in a database (hosted on its behalf by EthicsPoint in the US) and may contact you for further information. You have a right of subject access to the personal information AstraZeneca processes about you.

THIS IS NOT AN EMERGENCY SERVICE

Reports submitted through this service may not receive an immediate response. If you require emergency assistance, please contact your local authorities.